Hongli Liu Selected Research

PF-6409577

10/2022

PF-06409577 inhibits renal cyst progression by concurrently inhibiting the mTOR pathway and CFTR channel activity.

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Hongli Liu Research Topics

Disease

32	Neoplasms (Cancer) 10/2022 - 04/2007
7	Uterine Cervical Neoplasms (Cancer of the Cervix) 01/2022 - 12/2010
7	Neoplasm Metastasis (Metastasis) 12/2021 - 02/2015
6	Colorectal Neoplasms (Colorectal Cancer) 01/2021 - 07/2016
5	Necrosis 01/2022 - 12/2007
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2022 - 01/2011
5	Carcinoma (Carcinomatosis) 12/2018 - 01/2011
4	Inflammation (Inflammations) 08/2022 - 01/2013
4	Lung Neoplasms (Lung Cancer) 01/2022 - 01/2011
4	Hepatocellular Carcinoma (Hepatoma) 01/2022 - 01/2016
4	Prostatic Neoplasms (Prostate Cancer) 01/2017 - 12/2015
3	Rectal Neoplasms (Rectal Cancer) 11/2021 - 12/2018
3	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 05/2020
3	Tauopathies 01/2021 - 12/2019
2	Autosomal Dominant Polycystic Kidney (ADPKD) 10/2022 - 01/2022
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 08/2022 - 02/2015
2	1 Combined Deficiency Of Vitamin K-Dependent Clotting Factors 06/2022 - 08/2020
2	Kidney Diseases (Kidney Disease) 01/2022 - 01/2022
2	Stomach Neoplasms (Stomach Cancer) 01/2022 - 08/2021
2	Atrial Fibrillation 01/2022 - 01/2021
2	COVID-19 04/2021 - 01/2021
2	Obstructive Sleep Apnea 01/2021 - 01/2021
2	Adenocarcinoma of Lung 07/2020 - 01/2019
2	Glioblastoma (Glioblastoma Multiforme) 01/2020 - 06/2011
2	Virus Diseases (Viral Diseases) 01/2020 - 12/2014
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2020 - 12/2019
2	Squamous Cell Carcinoma of Head and Neck 01/2020 - 01/2020
2	Colonic Neoplasms (Colon Cancer) 12/2018 - 07/2016
2	Microsatellite Instability 12/2018 - 10/2018
2	Carcinogenesis 10/2018 - 07/2015
2	Thyroiditis 01/2018 - 01/2016
2	Cutaneous T-Cell Lymphoma (Lymphoma, T Cell, Cutaneous) 07/2015 - 02/2014
2	Rheumatoid Arthritis 01/2015 - 01/2010
2	Wounds and Injuries (Trauma) 03/2013 - 04/2007
2	Nasopharyngeal Neoplasms (Cancer of the Nasopharynx) 09/2011 - 02/2011
1	Sepsis (Septicemia) 11/2022
1	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 10/2022
1	Diabetic Nephropathies (Diabetic Nephropathy) 10/2022
1	Cysts 10/2022

Drug/Important Bio-Agent (IBA)

16	Proteins (Proteins, Gene)FDA Link 10/2022 - 01/2006
7	DNA (Deoxyribonucleic Acid)IBA 01/2022 - 11/2013
6	Biomarkers (Surrogate Marker)IBA 08/2022 - 02/2011
4	Pharmaceutical PreparationsIBA 10/2022 - 12/2014
4	C-Reactive ProteinIBA 01/2021 - 01/2017
4	2-5A-dependent ribonuclease (RNase L)IBA 01/2020 - 01/2007
4	Androgen Antagonists (Antiandrogens)IBA 01/2017 - 12/2015
3	Vitamin K FDA Link 06/2022 - 08/2020
3	Biological ProductsIBA 06/2022 - 06/2016
3	MicroRNAs (MicroRNA)IBA 01/2021 - 01/2010
3	LigandsIBA 01/2020 - 12/2010
3	CateninsIBA 10/2019 - 02/2015
3	Reactive Oxygen Species (Oxygen Radicals)IBA 02/2019 - 12/2016
3	Androgen Receptors (Androgen Receptor)IBA 01/2017 - 12/2015
3	bicalutamide (Casodex)FDA LinkGeneric 01/2017 - 12/2015
3	Histone Deacetylases (Histone Deacetylase)IBA 07/2015 - 01/2006
2	Therapeutic UsesIBA 08/2022 - 01/2020
2	Blood Coagulation Factors (Coagulation Factor)IBA 06/2022 - 08/2020
2	Glutamic Acid (Glutamate)FDA Link 06/2022 - 01/2019
2	Insulin (Novolin)FDA Link 01/2022 - 12/2014
2	16S Ribosomal RNAIBA 12/2021 - 01/2021
2	Microtubule-Associated Proteins (Microtubule-Associated Protein 2)IBA 01/2021 - 05/2020
2	AntigensIBA 01/2021 - 02/2011
2	Oxygen (Dioxygen)IBA 01/2021 - 09/2013
2	tau Proteins (tau Protein)IBA 01/2021 - 12/2019
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 10/2019
2	Messenger RNA (mRNA)IBA 01/2020 - 10/2010
2	InterferonsIBA 01/2020 - 12/2014
2	Carcinoembryonic AntigenIBA 12/2019 - 03/2018
2	Transforming Growth Factors (Transforming Growth Factor)IBA 02/2019 - 01/2013
2	Small Interfering RNA (siRNA)IBA 02/2019 - 12/2010
2	Oxidoreductases (Dehydrogenase)IBA 02/2019 - 07/2006
2	Interleukin-10 (Interleukin 10)IBA 12/2018 - 01/2013
2	Indicators and Reagents (Reagents)IBA 12/2018 - 11/2013
2	NucleotidesIBA 12/2018 - 10/2018
2	Interleukin-23 (Interleukin 23)IBA 01/2018 - 02/2015
2	squamous cell carcinoma-related antigenIBA 01/2017 - 02/2015
2	Histone Deacetylase InhibitorsIBA 07/2015 - 02/2014
2	Vorinostat FDA Link 07/2015 - 02/2014
2	CytokinesIBA 01/2015 - 08/2014
2	Immunoglobulins (Immunoglobulin)IBA 07/2014 - 11/2013
2	Immunoglobulin A (IgA)IBA 07/2014 - 02/2009
2	VaccinesIBA 02/2011 - 02/2009
2	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 05/2009 - 07/2006
2	theasinensin AIBA 01/2006 - 01/2006
2	trichostatin A (A 300)IBA 01/2006 - 01/2006
1	Metformin (Glucophage)FDA LinkGeneric 10/2022
1	Adenosine Monophosphate (AMP)IBA 10/2022
1	PF-6409577IBA 10/2022
1	Cystic Fibrosis Transmembrane Conductance Regulator (Protein, CFTR)IBA 10/2022
1	Protein Kinases (Protein Kinase)IBA 10/2022

Therapy/Procedure

7	Therapeutics 10/2019 - 07/2006
5	Radiotherapy 11/2021 - 02/2011
5	Drug Therapy (Chemotherapy) 11/2021 - 05/2009
3	Immunotherapy 01/2022 - 01/2014
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 01/2022 - 01/2021
2	Aftercare (After-Treatment) 08/2021 - 02/2015
2	Neoadjuvant Therapy 01/2021 - 12/2018
2	Off-Pump Coronary Artery Bypass (Coronary Artery Bypass, Off Pump) 01/2021 - 01/2021
1	Length of Stay 11/2022
1	Total Parenteral Nutrition 11/2022